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Research Portals

Affiliated Sites




National Center for Microscopy and Imaging Research (NCMIR)
Center for Research in
Biological Systems
Basic Science Building, Room 1000
University of California, San Diego
9500 Gilman Drive
Dept. Code 0608
La Jolla, CA 92093-0608 USA
Voice: (858) 534-0276
Fax: (858) 534-7497

Journal Covers

Below are recent journal covers featuring NCMIR images. View additional covers in the archive.

Microscopy and Analysis cover
 

Microscopy and Analysis cover
 

Microscopy and Analysis cover
 

Microscopy and Analysis cover
 

Microscopy and Analysis cover
 

Microscopy and Analysis cover
 

Publications 2006

The multidisciplinary work of NCMIR researchers and their collaborators have been published in a variety of journals and presented in local, national, and international forums.

Articles

  1. Bang ML, Li X, Littlefield R, Bremner S, Thor A, Knowlton KU, Lieber RL and Chen J (2006) Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle. J Cell Biol 173(6):905-916.
  2. Barsoum MJ, Yuan H, Gerencser AA, Liot G, Kushnareva Y, Graber S, Kovacs I, Lee WD, Waggoner J, Cui J, White AD, Bossy B, Martinou JC, Youle RJ, Lipton SA, Ellisman MH, Perkins GA and Bossy-Wetzel E (2006) Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. Embo J. 25(16):3900-3911.
  3. Beahm DL, Oshima A, Gaietta GM, Hand GM, Smock AE, Zucker SN, Toloue MM, Chandrasekhar A, Nicholson BJ and Sosinsky GE (2006) Mutation of a conserved threonine in the third transmembrane helix of alpha- and beta-connexins creates a dominant-negative closed gap junction channel. J Biol Chem 281(12):7994-8009.
  4. Bokil H, Tchernichovsky O and Mitra PP (2006) Dynamic phenotypes: time series analysis techniques for characterizing neuronal and behavioral dynamics. Neuroinformatics 4(1):119-128.
  5. Bumbarger DJ, Crum J, Ellisman MH, Baldwin JG. 2006. Three-dimensional reconstruction of the nose epidermal cells in the microbial feeding nematode, Acrobeles complexus (Nematoda: Rhabditida). J Morphol. 267(11):1257-1272..
  6. Chow SK, Hakozaki H, Price DL, Maclean NA, Deerinck TJ, Bouwer JC, Martone ME, Peltier ST and Ellisman MH (2006) Automated microscopy system for mosaic acquisition and processing. J Microsc 222(Pt 2):76-84.
  7. De Jaco A, Comoletti D, Kovarik Z, Gaietta G, Radic Z, Lockridge O, Ellisman MH, Taylor P (2006) A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha, beta hydrolase-fold protein family. J Biol Chem 281(14):9667-9676.
  8. Everts M, Saini V, Leddon JL, Kok RJ, Stoff-Khalili M, Preuss MA, Millican CL, Perkins G, Brown JM, Bagaria H, Nikles DE, Johnson DT, Zharov VP and Curiel DT (2006) Covalently linked Au nanoparticles to a viral vector: potential for combined photothermal and gene cancer therapy. Nano Lett 6(4):587-591.
  9. Frey TG, Perkins GA, Ellisman MH (2006) Electron Tomography of Membrane-Bound Cellular Organelles. Annu Rev Biophys Biomol Struct 35:199-224.
  10. Gaietta GM, Giepmans BN, Deerinck TJ, Smith WB, Ngan L, Llopis J, Adams SR, Tsien RY, Ellisman MH (2006) Golgi twins in late mitosis revealed by genetically encoded tags for live cell imaging and correlated electron microscopy. Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17777-17782.
  11. Giepmans BN (2006) Role of connexin43-interacting proteins at gap junctions. Adv Cardiol 42:41-56.
  12. Giepmans BNG, SR Adams, MH Ellisman, and RY Tsien (2006) The fluorescent toolbox for assessing protein location and function. Science 312:(5771):217-224.
  13. Lawrence A, Bouwer JC, Perkins G and Ellisman MH (2006) Transform-based backprojection for volume reconstruction of large format electron microscope tilt series. J Struct Biol 154(2):144-167.
  14. Lin A, Peltier S, Grethe J and Ellisman M Case studies on the use of workflow technologies for scientific analysis, in Scientific Workflows for eScience (Taylor IJ, Deelman E, Gannon DB and Shields MS eds), Springer Publishing, New York. in press
  15. Moisan TA, MH Ellisman, CW Buitenhuys and GA Sosinsky (2006) Differences in chloroplast ultrastructure of Phaeocystis antarctica in low and high light. Marine Biology 149(6):1281-1290
  16. Price DL, Chow SK, MacLean NAB, Hakozaki H, Peltier S, Martone ME, Ellisman MH (2006) High-Resolution Large-Scale Mosaic Imaging using Multiphoton Microscopy to Characterize Transgenic Mouse Models of Human Neurological Disorders. Neuroinformatics 4(1):65-80.
  17. Smalheiser NR, Torvik VI, Bischoff-Grethe A, Burhans LB, Gabriel M, Homayouni R, Kashef A, Martone ME, Perkins GA, Price DL, Talk AC, West R. (2006) Collaborative development of the Arrowsmith two node search interface designed for laboratory investigators. J Biomed Discov Collab. 1(1):
  18. Wilhelmsson U, Bushong EA, Price DL, Smarr BL, Phung V, Terada M, Ellisman MH, Pekny M (2006) Redefining the concept of reactive astrocytes as cells that remain within their unique domains upon reaction to injury. Proc Natl Acad Sci 103(46):17513-17518.

Abstracts

  1. Ambrosi C, A Oshima, A Smock, J Brown, GE Sosinsky (2006) Structural Analysis of Connexin26 Wild Type and Mutant Gap Junctions and Hemichannels. 46th Annual Meeting of the American Society of Cell Biology, San Diego, CA Dec 9-13, 2006.
  2. Bielas SL, F Serneo, M Chechlacz, T Deerinck, P Allen, MH Ellisman, J Gleeson (2006) Spinophilin Facilitates PP1-mediated Dephosphorylation of PSer297 Doublecortin in Microtubule Bundling at the Axonal “Wrist” 46th Annual Meeting of the American Society of Cell Biology, San Diego, CA Dec 9-13, 2006.
  3. Bippes CA, J Yu, GM Hand, DJ Muller, GE Sosinsky (2006) Connexin26 Hemichannels Close at Their Extracellular Surface by a Combination of Low pH and Aminosulfonates. 46th Annual Meeting of the American Society of Cell Biology, San Diego, CA Dec 9-13, 2006.
  4. Bippes C, Jinshu Yu, G Hand, A Smock, D Müller and G Sosinsky (2006) Calcium and pH Induced Closure of Gap Junction Hemichannels as Visualized by Atomic Force Microscopy. Paper presented at the 16th International Congress on Microscopy (ICM) Sapporo, Japan, September 3-6, 2006. [PDF]
  5. Boassa D, G Gaietta, J Hu, R Bruzzone, G Dahl, GE Sosinsky (2006) Glycosylation Affects Plasma Membrane Targeting of Pannexin 1 Channels. 46th Annual Meeting of the American Society of Cell Biology, San Diego, CA Dec 9-13, 2006.
  6. Boline JK, AA Mackenzie-Graham, DW Shattuck, H Yuan, SP Anderson, DM Sforza J Wang, RW Williams, W Wong, ME Martone, I Zaslavsky, AW Toga 2006. A digital atlas and neuroinformatics framework for query and display of disparate data. Society for Neuroscience Conference, Atlanta, Oct 14, 2006
  7. Bug WJ, A Gupta, C Gustafson, ME Martone, J Nissanov, WW Wong, I Zaslavsky 2006. Integrating brain atlas tools for broad-field morphometric analysis and semantic data integration. Society for Neuroscience Conference, Atlanta, Oct 16, 2006
  8. Burette AC, J Crum, ME Martone, MH Ellisman, RJ Weinberg 2006. The architecture of the presynaptic active zone. Society for Neuroscience Conference, Atlanta, Oct 16, 2006
  9. Burette AC, J Crum, ME Martone, MH Ellisman, RJ Weinberg 2006. The architecture of the presynaptic active zone. 4th Intl. Congress on Electron Microscopy, Nov 5-8, San Diego, CA.
  10. Coggan JS, CL Lopreore, TM Bartol, DX Keller, GE Sosinsky, TJ Sejnowski, MH Ellisman 2006. Compartment and electrodiffusion models of myelinated axon conduction reliability. Society for Neuroscience Conference, Atlanta, Oct 16, 2006
  11. Ellisman, M.H. (2006) Multi-scale Imaging and Multi-scale Modeling of the Nervous System Using 3D Views of the Brain Obtained with High Energy Electron Microscopy, IMC 16th International Microscopy Conference, September 2006, Sapporo, Japan.
  12. Garcia ML, CS Lobsiger, K Yamanaka, J Fujimoto, J Crum, MH Ellisman, NA Calcutt, DW Cleveland (2006) Gene Replacement Reveals Neurofilament Dependent Axonal Growth and Acceleration of ALS-like Motor Neuron Disease Is Independent of the Known Myelin-dependent Phosphorylation of Neurofilament Tail Domains. 46th Annual Meeting of the American Society of Cell Biology, San Diego, CA Dec 9-13, 2006.
  13. Gerencser AA, H. Yuan, M J Barsoum, G Liot, S Graber, Y Kushnareva, J Cui, I Kovacs, W Lee, J Waggoner, B Bossy, J Martinou, RJ Youle, SA Lipton, MH Ellisman, GA Perkins, E Bossy-Wetzel 2006 "Nitric oxide induces mitochondrial fission regulated by dynamin-related GTPases" Society for Neuroscience Conference, Atlanta, Oct 14, 2006
  14. Giepmans B, Thomas Deerinck, Benjamin Smarr, Ying Jones, Shalini Ananda, John Crum, Gina Sosinsky & Mark Ellisman. (2006) Quantum Dots for protein identification in light microscopy and EM-tomography. 4th Intl. Congress on Electron Microscopy, Nov 5-8, San Diego, CA
  15. Fong L, L Chen, R West, M Wong, S Lamont, A Gupta, and M Martone 2006 “Imaging Annotation For Electron Tomographic Data”, 4th Intl. Congress on Electron Microscopy, San Diego, Nov. 5-8, 2006
  16. Fong L, L Chen, R West, A Gupta, S Lamont ME Martone 2006. OntoQuest: a dynamic knowledge base for neuroscience. Society for Neuroscience Conference, Atlanta, Oct 14, 2006
  17. Gardner D, GA Ascoli, ME Martone, GM Shepherd, PW Sternberg 2006. Toward the Neuroscience Information Framework. Society for Neuroscience Conference, Atlanta, Oct 14, 2006
  18. Gupta A, C Bean, W Bug, C Fennema-Notestine, ME Martone, JA Turner, JS Grethe 2006. Creating a community-based knowledge management framework for integrating neuroscience data via ontologies. Society for Neuroscience Conference, Atlanta,Oct 14, 2006
  19. Jin L, M Ellisman, P Leblanc, F Duttweiler, J Bouwer, S Peltier, A-C Milazzo, N-H Xuong, S Kleinfelder, and S Li. (2006) A new direct detection detector for electron microscopy. 4th Intl. Congress on Electron Microscopy, Nov 5-8, San Diego, CA
  20. Johnson J, G Perkins, J Brown, P Lahsaei, S Ghassemzadeh, M Ellisman, and D Fox. (2006) A Three-Dimensional Electron Tomographic Analysis of Rod Photoreceptor Synaptic Terminal Mitochondria in Control, Lead-Exposed, and/or Bcl-xL Transgenic Mice. May 1, ARVO Meeting Fort Lauderdale, Florida.
  21. Konur S, J Kim, T Deerinck, M Ellisman, A Ghosh 2006 Regulation of spine morphogenesis by NMDAR signaling. Society for Neuroscience Conference, Atlanta, Oct 16, 2006
  22. Lanman J, J Crum, G Sosinsky, M Ellisman, A Schneemann, and JE Johnson. (2006) Visualizing the spatial and temporal relationship of virus entry and assembly in cells. 4th Intl. Congress on Electron Microscopy, Nov 5-8, San Diego, CA
  23. Lathers, Su, Kulungowski, Lin, Mehta, Peltier, Deelman, and Ellisman. (2006) Enabling Parallel Scientific Applications with Workflow Tools. Challenges of Large Applications in Distributed Environments (CLADE) Workshop, June 19, Paris France.
  24. Lichtenstein A, PJ Minogue, G Gaietta, GE Sosinsky, EC Beyer, VM Berthoud (2006) Autophagy: A Novel Degradation Pathway for Connexins. 46th Annual Meeting of the American Society of Cell Biology, San Diego, CA Dec 9-13, 2006.
  25. Lin A, M Su, A Kulungowski, A Lathers, G Mehta, S Peltier, E Deelman, and M Ellisman. (2006) Cyberinfrastructure for parallel tomographic reconstruction and analysis. 4th Intl. Congress on Electron Microscopy, Nov 5-8, San Diego, CA
  26. Niikura Y, R Scott, GA Perkins, K Kitagawa (2006) BUB1, a Spindle Checkpoint Kinase, Determines the Fate of Cells with Mitotic Errors by Inducing Caspase-independent Mitotic Cell Death. 46th Annual Meeting of the American Society of Cell Biology, San Diego, CA Dec 9-13, 2006.
  27. Oshima A, K Tani, Y Hiroaki, Y Fujiyoshi, GE Sosinsky (2006) Projection Structure at 7Å Resolution and Initial 3D Map of a Human Connexin26. 46th Annual Meeting of the American Society of Cell Biology, San Diego, CA Dec 9-13, 2006.
  28. Oshima A, K Tani, Y Hiroaki, Y Fujiyoshi and GE Sosinsky (2006) Two Dimensional Crystallization and Projection Structure of a Human Connexin26. Paper presented at annual meeting of the Microscopy Society of America (MSA), Chicago , July 30-August 3, 2006. [PDF]
  29. Perkins G, J Brown, P Lahsaei, S Ghassemzadeh, M Ellisman, J Johnson, and D Fox (2006) Overexpression Protects Rod Photoreceptor Synaptic Terminal Mitochondria From Lead-Induced Permeability Transition. Society of Toxicology Meeting, March 8, 2006 San Diego, CA
  30. Perkins, GA, AD White, JM Brown, A Dixit, RT Scott, R Wagner, I Wu, MHEllisman, and GA Spirou 2006 "Electron Tomography Reveals Novel Features of the Mitochondrial Associated Adherens Complex" 4th Intl. Congress on Electron Microscopy, San Diego, Nov. 6, 2006
  31. Price DL, E Rockenstein, V Phung NAB Maclean, E Masliah, MH Ellisman 2006 A Parkinsonian mouse model overexpressing alpha-synuclein: assessment of changes in behavior and glutamate and dopamine receptor immunoreactivity. Society for Neuroscience Conference, Atlanta, Oct 14, 2006
  32. Sargis J and M Martone. (2006) The Cell Centered Database–developing smart tools to improve access to and integration and organization of a light and electron microscopy data management system. 4th Intl. Congress on Electron Microscopy, Nov 5-8, San Diego, CA
  33. Sosinsky, GE and SJ Ludtke (2006) Hybrid Three-Dimensional Reconstruction Methodology for Obtaining Structural Information of Locally Ordered Connexin26 Gap Junction Lattices. Paper presented at annual meeting of the Microscopy Society of America (MSA), Chicago, July 30-August 3, 2006. [PDF]
  34. Sosinsky G, M Tihova, Y-M Kim, T Deerinck, S Ghassemzadeh, C Carr, and M Ellisman. (2006) 3-D architecture of nuclear laminaris Nodes of Ranvier from the auditory system of the barn owl. 4th Intl. Congress on Electron Microscopy, Nov 5-8, San Diego, CA
  35. Sun M, J Williams, D Green, G Perkins, J Brown, M Ellisman, and T Frey. (2006) Correlated light and electron microscopy/tomography reveals changes in mitochondria during release of cytochrome c. 4th Intl. Congress on Electron Microscopy, Nov 5-8, San Diego, CA
  36. Turner JA, C Fennema-Notestine, ME Martone, AR Laird, JS Grethe, W Bug, A Gupta, C Bean 2006 “You say potato, I say potahto: ontological engineering applied within the Biomedical Informatics Research Network” Society for Neuroscience Conference, Atlanta, Oct 14, 2006
  37. West R. (2006) Artistic Approaches to High-Dimensional Visualization, Association for Laboratory Automation, January 24, 2006. Palm Springs, CA.
  38. Yamaguchi R, Andreyev A, Murphy AN, Perkins GA, Ellisman MH and Newmeyer DD (2006) Mitochondria frozen with trehalose retain a number of biological functions and preserve outer membrane integrity. Cell Death Differentiation.

Monday, 18-Aug-2008 14:10:26 PDT