Research Highlights

It's Not What You Eat But When You Eat

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June 2012 La Jolla

Researchers at the Salk Institute led by Dr. Satchidananda Panda with NCMIR collaborators, published a provocative paper In the June issue of Cell Metabolism showing that mice fed a high calorie/high fat diet on a time restricted feeding schedule were protected against obesity and related complications compared to mice eating the same amount of calories ad libitum. These results suggest that time restricted feeding could be a non-pharmacological intervention in humans that could prevent obesity and its associated metabolic disorders. Serial block face SEM imaging and analysis for this study was performed at NCMIR.


Citation: Hatori M., Vollmers C., Zarrinpar A., DiTacchio L., Bushong E. A., Gill S., Leblanc M., Chaix A., Joens M., Fitzpatrick J. A., Ellisman M. H., Panda S. (2012). Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell Metab 15:848-860.

Online version of the article in Cell Metabolism